000 02227cam a2200301 i 4500
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008 120822s2013 enka b 001 0 eng
010 _a 2012947637
020 _a9780199697397 (pbk.)
040 _aDLC
_beng
_cDLC
_erda
042 _apcc
050 0 0 _aRS403
_b.P38 2013
082 0 0 _a615.1/9
_223
100 1 _aPatrick, Graham L.
245 1 3 _aAn introduction to medicinal chemistry /
_cGraham L. Patrick.
250 _aFifth edition.
260 _aOxford
_bOxford University Press
_cc2013
300 _axxiii, 789 pages :
_billustrations (some color) ;
_c25 cm.
504 _aIncludes Bibliographical references and Index
505 _a Drugs and drug targets an overview Drug targets : structure and function Protein structure and function Enzymes: structure and function Receptors: structure and function Receptors and signal transduction Nucleic acids: structure and function Pharmacodynamics and pharmacokinetics Enzymes as drug targets Receptors as drug targets Nucleic acids as drug targets Miscellaneous drug targets Pharmacokinetics and related topics Statins Drug discovery, design, and development Drug discovery: finding a lead Drug design: optimizing target interactions Drug design: optimizing access to the target Getting the drug to market The design of ACE inhibitors Artemisinin and related antimalarial drugs The design of oxamniquine Tools of the trade Combinatorial synthesis Computers in medicinal chemistry Quantitative structure-activity relationships (QSAR) De novo design of a thymidylate synthase inhibitor Selected topics in medicinal chemistry Antibacterial agents Antiviral agents Anticancer agents Cholinergics, anticholinergics, and anticholinesterases Drugs acting on the adrenergic nervous system Opioid analgesics Antiulcer agents Steroidal anti-inflammatory agents Design of a novel antidepressant
650 0 _aPharmaceutical chemistry.
906 _a7
_bcbc
_corigcop
_d2
_eepcn
_f20
_gy-gencatlg
942 _2lcc
_cBK
_xLL
999 _c14553
_d14553