Breast cancer : treatment and prognosis/ Basil Arnold Stoll

includes bibliographical references and index

Part 1: Impact of current treatment : Surgery - prolonged survival or cure; Radiotherapy - prolonged survival or local control?; Systemic therapy - prolonged survival or growth control?; Clonal heterogeneity and its implications; Role of randomized trials; Decision making in primary therapy; Decision making in palliative therapy; Psychological impact on the patient. Part 2: Pointers to prognosis : Components of a prognostic index; Histopathology cytometry in prognosis; Steroid receptor assay and prognosis; Steroid metabolism in breast cancer; Age group and cancer prognosis; Nutritional factors and prognosis; Metabolic diseases influencing prognosis; Immune reactivity and prognosis. Part 3: Prospects for new approaches : Targeting of systemic agents; Stem cells and clonogenic assays; Assessing response to systemic therapy; Can progression to autonomy be delayed?; Can metastasis be restrained?; Can tumour maturation be induced?; Local growth factors and tumour stimulation.