TY  - BOOK
AU  - Rowland,Malcolm
AU  - Tozer,Thomas N.
AU  - Rowland,Malcolm
TI  - Clinical pharmacokinetics and pharmacodynamics: concepts and applications 
SN  - 9780781750097
AV  - RM301.5.R68 2011 
PY  - 2011///
CY  - Philadelphia
PB  - Lippincott William & Wilkins
KW  - Pharmacokinetics
KW  - Chemotherapy
KW  - Drug Therapy
N1  - Rev. ed. of: Clinical pharmacokinetics. 1995; Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data
ER  -