TY  - BOOK
AU  - Verstreken,Patrik
TI  - Parkinson's disease : molecular mechanisms underlying pathology
SN  - 9780128037836
AV  - RC382.P24 2017 
U1  - 616.8/33 23
PY  - 2017///
CY  - London : 
PB  - Elservier, 
KW  - Parkinson's disease
KW  - Molecular aspects
KW  - Parkinson Disease
KW  - physiopathology
N1  - Includes bibliographical references and index; The neurogenetics of Parkinson's Disease and putative links to other neurodegenerative disorders / C.M. Lill, C. Klein -- Electron transport train / L. Aerts, V.A. Morais -- Mitochondrial fission and fusion / V.L. Hewitt, A.J. Whitworth -- Axonal mitochondrial transport / E. Shlevkov, T.L. Schwarz -- Mitophagy / L. King, H. Plun-Favreau -- Autophagy / P.A. Lewis, M. Perez-Carrion, G. Piccoli -- Endocytosis and synaptic function / S.F. Soukup, P. Verstreken, S. Vilain -- Neuroinflammation as a potential mechanism underlying Parkinsons Disease / C. Cebrián, D. Sulzer -- Protien translation in Parkinson's Disease / J.W. Kim, L. Abalde-Atristain, H. Jia, I. Martin, T.M. Dawson, V.L. Dawson
N2  - Parkinson's Disease: Molecular Mechanisms Underlying Pathology explores the molecular pathways at the basis of the cellular defects connected to Parkinson's disease, the second most common neurodegenerative disease, and the most common movement disorder. This book presents the latest research on the pathways and mechanisms that have been discovered to play a role in Parkinson's pathology. This focus on mechanisms rather than individual genes allows the contributors to elaborate on overlapping and joint functions of different causative genes. Readers will find descriptions of model systems that present parallels (and differences) between discoveries in different species, demonstrating the importance of multidisciplinary research that spans a broad array of technologies and model organisms. Written from both a cross-methodology and cross-species perspective, the book provides readers with the current state of knowledge on the molecular biology of Parkinson's
ER  -