Tietz fundamentals of clinical chemistry and molecular diagnostics / [Edited by] Carl A. Burtis, David E. Bruns.

"On behalf of the worldwide community of clinical laboratorians, we are pleased to dedicate this edition of the Tietz fundamentals of clinical chemistry and molecular diagnostics to Professor Norbert W. Tietz, PhD."--Page v.
Publié à l'origine sous le titre : Fundamentals of clinical chemistry / edited by Norbert W. Tietz, c1970.
Gwendolyn A. McMillin, Carl A. Burtis and David E. Bruns.

Includes bibliographical references and index.

CONTENTS
PART I PRINCIPLES OF LABORATORY MEDICINE
1. Clinical chemistry, molecular diagnostics, and laboratory medicine / David E. Bruns, Francois A. Rousseau, and Carl A. Burtis --
2. Selection and analytical evaluation of methods -- with statistical techniques / Kristian Linnet, and James C. Boyd --
3. Clinical evaluation of methods / Edward R. Ashwood and David E. Bruns --
4. Evidence-based laboratory medicine / Christopher P. Price, Patrick M.M. Bossuyt, and David E. Bruns --
5. Establishment and use of reference values / Gary L. Horowitz --
6. Specimen collection, processing, and other preanalytical variables / Doris M. Haverstick and Amy R. Groszbach --
7. Quality management / George G. Klee, and James O. Westgard --
8. Principles of basic techniques and laboratory safety / Stanley F. Lo --
PART II ANALYTICAL TECHNIQUES AND INSTRUMENTATION
9. Optical techniques / L.J. Kricka and Jason Y. Park --
10. Electrochemistry and chemical sensors / Paul D'Orazio and Mark E. Meyerhoff --
11. Electrophoresis / Lindsay A.L. Bazydlo and James P. Landers --
12. Chromatography. Glen L. Hortin, and Carl A. Burtis --
13. Mass Spectrometry / Alan L. Rockwood, Thomas M. Annesley and Nicholas E. Sherman --
14. Enzyme and rate analyses / Renze Bais and Mauro Panteghini --
15. Immunochemical techniques / L.J. Kricka and J.Y. Park --
16. Automation / James C. Boyd and Charles D. Hawker --
17. Point-of-care instrumentation / Christopher P. Price, and Andrew St. John --
PART III ANALYTES
18. Amino acids, peptides and proteins / Glen L. Hortin --
19. Serum enzymes / Mauro Panteghini and Renze Bais --
20. Tumor markers and cancer genes / Lori J. Sokoll, Alex J. Rai and Daniel W. Chan --
21. Kidney function tests -- creatinine, urea, and uric acid / Edmund J. Lamb, and Christopher P. Price --
22. Carbohydrates / David B. Sacks --
23. Lipids, lipoproteins, apolipoproteins and other cardiac risk factors / Alan T. Remaley, Nader Rifai and G. Russell Warnick --
24. Electrolytes and blood gases / Mitchell G. Scott, Vicky A. LeGrys and Emily I. Schindler --
25. Hormones. Michael Kleerekoper --
26. Catecholamines and serotonin / Graeme Eisenhofer, Thomas G. Rosano and Ronald J. Whitley --
27. Vitamins, trace elements and nutritional assessment / Alan Shenkin and Norman B. Roberts --
28. Hemoglobin, iron and bilirubin / Trefor Higgins [and others] --
29. Porphyrins and porphyrias / Michael N. Badminton [and others] --
30. Therapeutic drugs and their management / Christine L.H. Snozek, Gwendolyn A. McMillin --
31. Clinical toxicology / Loralie Langman, Laura K. Bechtel, and Christopher P. Holstege --
32. Toxic metals / Thomas P. Moyer --
PART IV PATHOPHYSIOLOGY
33. Diabetes / David B. Sacks --
34. Cardiovascular disease / Fred S. Apple, Jens Peter Goetze, Allan S. Jaffe --
35. Kidney Disease / Michael P. Delaney, Christopher P. Price and Edmund J. Lamb --
36. Physiology and disorders of water, electrolyte, and acid-base metabolism / Emily I. Schindler, and Mitchell G. Scott --
37. Liver disease / D. Robert Dufour --
38. Gastrointestinal and pancreatic diseases. Peter G. Hill --
39. Disorders of bone and mineral metabolism / Juha Risteli [and others] --
40. Disorders of the pituitary / Ishwarlal Jialal, William E. Winter and Roger L. Bertholf --
41. Disorders of the adrenal cortex / Roger L. Bertholf, Ishwarlal Jialal, and William E. Winter --
42. Thyroid disorders / William E. Winter, Desmond Schatz, and Roger L. Bertholf --
43. Reproduction-related disorders / Mari L. DeMarco, and Ann M. Gronowski --
44. Pregnancy and prenatal testing / David G. Grenache and Geralyn Lambert-Messerlian --
45. Newborn screening and inborn errors of metabolism / Marzia Pasquali and Nicola Longo --
46. Pharmacogenetics / Gwendolyn A. McMillin --
PART V MOLECULAR DIAGNOSTICS
47. Principles of molecular biology / Y.M. Dennis Lo and Rossa W.K. Chiu --
48. Nucleic acid techniques and applications / Carl T. Wittwer and Noriko Kusukawa --
49. Genomes and nucleic acid variations / Carl T. Wittwer, and Noriko Kusukawa --
PART VI REFERENCE INFORMATION
Reference information for the clinical laboratory.

This text uses a laboratory perspective in providing the clinical chemistry fundamentals you need to work in a real-world, clinical lab. Coverage ranges from laboratory principles to analytical techniques and instrumentation, analytes, pathophysiology, and more. New content keeps you current with the latest developments in molecular diagnostics. This textbook shows how to select and perform diagnostic lab tests, and accurately evaluate results