Aulton's Pharmaceutics : The design and manufacture of medicines / Edited by Michael E. Aulton.

Includes bibliographical references and index.

What is 'pharmaceutics'? Design of dosage forms PART ONE: SCIENTIFIC PRINCIPLES OF DOSAGE FORM DESIGN *Dissolution and solubility *Properties of solutions *Rheology *Surface and interfacial phenomena *Disperse systems *Kinetics of product stability PART TWO: PARTICLE SCIENCE AND POWDER TECHNOLOGY *Solid-state properties *Particle size analysis *Particle size reduction *Particle size separation *Mixing *Powder flow. PART THREE: PHARMACEUTICAL MICROBIOLOGY AND STERILIZATION *Fundamentals of microbiology *Pharmaceutical applications of microbiological techniques *Action of physical and chemical agents on microorganisms *Principles of sterilization *Sterilization in practice PART FOUR: BIOPHARMACEUTICAL PRINCIPLES OF DRUG DELIVERY *Introduction to biopharmaceutics *Gastrointestinal tract - physiology and drug absorption *Bioavailability - physicochemical and dosage form factors *Assessment of biopharmaceutical properties *Dosage regimens PART FIVE: DOSAGE FORM DESIGN AND MANUFACTURE *Pharmaceutical preformulation *Solutions *Clarification *Suspensions and emulsions *Powders and granules *Granulation *Drying *Tablets and compaction *Modified-release peroral dosage forms *Coating of tablets and multiparticulates *Hard gelatin capsules *Soft gelatin capsules *Pulmonary drug delivery *Nasal drug delivery *Transdermal drug delivery *Wound dressings *Rectal and vaginal drug delivery *Delivery of pharmaceutical proteins *Packs and packaging *Microbial contamination, spoilage and preservation of medicines *Product stability and stability testing *Pharmaceutical plant design *Heat transfer and the properties and use of steam